QWO® is the first and only FDA-approved injectable for the treatment of moderate to severe cellulite in the buttocks of adult women. For most women, over time, their skin thins, fat cells enlarge and push against the skin, and the fibrous bands under the skin’s surface thicken and cause tension.  These factors working together cause cellulite’s signature dimples on the thighs and buttocks.

How QWO Works

QWO is made from enzymes called collagenases. These enzymes are thought to target the structural causes under the skin, where cellulite starts. It’s thought that QWO works by releasing fibrous bands, redistributing fat cells, and stimulating the growth of new collagen. How QWO works in moderate to severe cellulite is not fully understood.

QWO Clinical Data

Endo Aesthetics conducted the largest clinical trials in the history of cellulite investigation to help determine the safety and efficacy of QWO. These two identical trials enrolled 845 women in the United States, aged 18 or older, with moderate to severe cellulite in the buttocks. Reductions in cellulite severity were observed more frequently in the QWO group compared to the placebo group as measured by the investigator and patient cellulite severity scales.

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QWO Quick Facts

  • First and only FDA-approved injectable for the treatment of moderate to severe cellulite in women's buttocks.
  • A non-surgical treatment performed in a doctor’s office or Medi Spa.
  • Injections take about 15-20 minutes or less.
  • Three treatment visits over the course of two months is typical. 
  • It has been studied on all skin types and ethnicities.

QWO may cause serious allergic reactions, including anaphylaxis and injection site bruising. Please see Important Safety Information below for more details.

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Dr. Keith Neaman, Dr. Dustin Christiansen, and the team at Neaman Medi Spa offer a variety of skin and body services to help you look and feel like the best version of yourself. Our non-surgical procedures can help you achieve your aesthetic goals without downtown or surgery. Contact our office today to schedule a consultation with the team at Neaman Medi Spa.

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I have been a regular client of the medi spa and cannot rant and rave enough about all the staff!! I love my visits with Tori and facial treatments. Tori is very professional and full of expertise on all my skin needs. I have highly recommended Tori to all my friends and family. My skin has never looked better!!!!

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Cellulite FAQ's

What is cellulite?

What causes cellulite?

Who gets cellulite?

Why aren't men prone to developing cellulite?

How does age impact the appearance of cellulite?

Are fat and cellulite the same?

Can weight loss help to get rid of cellulite?

What body parts are most prone to cellulite?

Do topical treatments help decrease the appearance of cellulite?

Why does treating cellulite matter?

What is cellulite?

Cellulite is a localized alteration (commonly referred to as a “dimple) in the contour of the skin that has been reported in approximately 90% of adult women of all races and ethnicities.

What causes cellulite?

Over time, three completely normal things can happen. Fat cells get larger, skin gets thinner and a little looser and the fibrous bands under the skin’s surface get thicker, leading to a dimpled appearance.

Who gets cellulite?

Women are more likely to have cellulite than men, and it affects women of all shapes, sizes, ages and races.

Why aren't men prone to developing cellulite?

Men have thicker skin than women do, and their collagen bands are oriented in a crisscross fashion, essentially eliminating the ability of the fat lobules to bulge through. If a man is given estrogen hormones (as in some cancer treatments), they can develop cellulite if there is enough fat.

How does age impact the appearance of cellulite?

Skin laxity happens as you age and can impact the appearance of cellulite.

Are fat and cellulite the same?

Fat is not cellulite and does not cause it, but fat cells getting bigger between fibrous bands under the skin can contribute to a bumpy appearance.

Can weight loss help to get rid of cellulite?

Weight loss might reduce the appearance of cellulite but won’t get rid of it since it doesn’t address the fibrous bands under the skin’s surface.6 In some cases, weight loss can actually make cellulite look worse because of resulting skin laxity.

What body parts are most prone to cellulite?

In an online Harris Poll survey of 2,006 women with cellulite, respondents said their cellulite was most commonly present in certain areas: 81% thighs, 66% butt, 42% stomach, 33% hips, 24% arms, 11% calves.8 Although cellulite can develop in various areas of the body, it mainly affects women and the predominant localization is on thighs and buttocks. This is because women tend to have more fatty deposits in these areas.

Do topical treatments help decrease the appearance of cellulite?

Topical treatments such as lotions, creams and scrubs have been used to temporarily reduce the appearance of cellulite.

Why does treating cellulite matter?

Cellulite isn’t just a superficial problem—it’s actually quite deep. According to a recent Harris Poll online survey of 2,006 women, nearly half said they are bothered “a great deal” or “a lot” by their cellulite.

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QWO Treatment FAQ's

What is Qwo®?

How does QWO work?

Is QWO a surgical procedure?

How do I know if QWO is right for me?

Can QWO be used to treat cellulite in other areas besides the buttocks?

How many treatments will I need?

Are there side effects of QWO?

What is Qwo®?

QWO is the first and only FDA-approved injectable for the treatment of moderate to severe cellulite in the buttocks of adult women.

How does QWO work?

Enzymes called collagenases target the structural causes under the skin, where cellulite starts. It’s thought that QWO works by releasing fibrous bands, redistributing fat cells, and stimulating the growth of new collagen. How QWO works in moderate to severe cellulite is not fully understood.

Is QWO a surgical procedure?

No. QWO is an injectable treatment option that is thought to target a primary structural cause of cellulite—the fibrous septae.1,2 The exact mechanism for the treatment of moderate to severe cellulite is unknown.

How do I know if QWO is right for me?

Your medical provider, such as our Licensed Nurse Injectors at Neaman Medi Spa, will determine if you are an appropriate candidate for QWO.

Can QWO be used to treat cellulite in other areas besides the buttocks?

QWO is only approved for treatment of moderate to severe cellulite in the buttocks of adult women. Endo Aesthetics is continuing to investigate additional areas of treatment.

How many treatments will I need?

Each treatment visit may include up to two treatment areas. QWO injections will be given three weeks apart for a total of three treatment visits.

Are there side effects of QWO?

There are risks associated with this product. QWO may cause serious side effects including: allergic (hypersensitivity) reactions, including anaphylaxis, and injection site bruising. These are not all the side effects of QWO.

QWO Safety Information

Do not receive QWO if you: are allergic to collagenase or to any of the ingredients in QWO, or have an active infection at the treatment area.

QWO may cause serious side effects, including:

  • Allergic (hypersensitivity) reactions, including anaphylaxis. Call your healthcare provider right away if you have hives, trouble breathing, low blood pressure, swollen face, chest pain, dizziness, or fainting after receiving QWO;
  • Injection site bruising

Before receiving QWO, tell your healthcare provider if you:

  • have a bleeding problem
  • are pregnant or may become pregnant, nursing or plan to nurse. You and your healthcare provider should decide if you will receive QWO or breastfeed.

Tell us about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell us if you take a medicine that prevents the clotting of your blood (antiplatelet or anticoagulant). The most common side effects of QWO include injection site bruising, pain, areas of hardness, itching, redness, discoloration, swelling, and warmth in the treatment area. These are not all the possible side effects of QWO. Call your healthcare provider for medical advice about side effects. You are encouraged to report the side effects of prescription drugs to the FDA at www.fda.gov/medwatch or 1-800-FDA-1088.

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Qwo Treatment at Neaman Medi Spa

At Neaman Medi Spa, we pride ourselves on offering only the safest and effective treatment modalities. QWO Treatment is comfortable and has been proven to be safe and effective. Developing a treatment plan that will adequately achieve the results you are looking for is our top priority. If you would like to improve your skin and reduce the appearance of cellulite, please contact Neaman Medi Spa and schedule your consultation with one of our highly-trained nurse injectors. We welcome patients from Portland, Salem, Eugene, and across Oregon.

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